Relation between TSA1 gene and biosynthesis of glucosinolates ”secondary sulfur compounds in Brassicaceae family”

Document Type : Research Paper

Authors

1 Assistant Professor, Department of Molecular and Cell Biology, Faculty of Basic Science, University of Mazandaran, Babolsar, Iran.

2 Assistant Professor, Department of Biology, Faculty of Basic Science, University of Mazandaran, Babolsar, Iran.

3 Professor, Laboratory of Plant Physiology, Faculty of Science and Engineering, University of Groningen, Groningen, the Netherlands.

Abstract

Glucosinolates are a potential target for genetic manipulation in crop improvement programs, due to their diverse roles in animal nutrition, plant defense against pests and pathogens, beneficial treatment effects in cancer, cardiovascular and neurological diseases. To date, more than 30 genes which are involved in biosynthesis of glucosinolates have been identified in Arabidopsis thaliana. During biotic and abiotic stresses, glucosinolate biosynthesis is further controlled by a complex network of transcription factors. Receptor-like kinases (RLKs) are proteins which act as cell surface receptors perceiving developmental and environmental signals in plants. Following functional studies of a RLKs (AT2G37050) in Arabidopsis thaliana, our previous proteomic data showed that 22 proteins such as TSA1, AT3G47570 and AT1G08750 were appeared in knockout of AT2G37050 while these proteins were not detected in wild type plant (unpublished data). The analysis resulted from GeneMANIA algorithm revealed biological connections between these three genes and glucosinolate biosynthesis pathway genes as well as regulating genes of glucosinolate biosynthesis pathway. Since glucosinolates are considered as sulfur containing secondary compounds in Arabidopsis thaliana and Brassicaceae family, biological connections between TSA1 and AT3G47570 with sulfur transporter genes as well as sulfur assimilation pathway genes will support more the role of these two genes on regulation of glucosinolates biosynthesis pathway.

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Main Subjects

References

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