Document Type : Review
Authors
1
Department of Environment, Materials and Energy Research Institute
2
Faculty of Entrepreneurship, University of Tehran
3
Genetics, Faculty of Agriculture, University of Kurdistan
4
استادیار زیست شناسی، دانشکده علوم، دانشگاه شیراز
10.30473/cb.2025.72719.1987
Abstract
In recent years, the extensive use of genetically modified products derived from genetic engineering technology has raised significant concerns regarding their biosafety, particularly in relation to food, human health, and the environment. This article aims to highlight the necessity of establishing a comprehensive risk assessment system at the macro level for genetically modified products, clarify the mechanisms underlying their potential risks, introduce various risk assessment approaches, and examine the essential tools required for designing such a system using large-scale system design methodologies. Given the complexity of this design process—which must account for artifacts, individuals, tools, processes, organizations, and the broader environment—the research adopts a qualitative, design-based methodology. This study explores three critical stages: identifying potential risks, elucidating the mechanisms of risk emergence, and designing appropriate assessment methods for genetically modified products. Based on these analyses, an integrated risk assessment framework that incorporates both micro- and macro-level perspectives is proposed. Ultimately, the establishment of robust evaluation and regulatory systems for genetically modified products, along with periodic reviews to ensure continuous improvement, must be prioritized in parallel with advancements in the scientific production and commercialization of these products.
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